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Ortega lab website

http://web.me.com/ortegaj_mcmaster/Ortega_lab_web_site/Welcome.html

The Spotlight – Under the Microscope…

After the successful graduation of three of our students this year, the Ortega lab is looking for two new graduate students to join the lab in the fall. Our lab works in understanding how the bacterial ribosome is assembled and also in the structure and function of bacterial proteases. These enzymes perform intracellular protein degradation, process that is involved in almost every aspect of the biology of the cell. These two articles below are an example of our most recent work in these areas.

• Jomaa et al. Understanding Ribosome Assembly: the Structure of in vivo Assembled Immature 30S Subunits Revealed by Cryo-electron Microscopy. (2011). RNA. Epub Feb 8,2011. Download article 1

• Li et al. Acyldepsipeptide Antibiotics Induces the Formation of a Structured Axial Channel in ClpP: a Model for the ClpX/ClpA Bound State of ClpP. (2010). Chemistry and Biology. 17: 959-969.Download article 2

If you are a motivated student, willing to make a serious contribution to research and looking for prime training in biochemistry, stop by our lab or drop a line to Dr. Joaquin Ortega (ortegaj@mcmaster.ca).

Article from GenomeBiology